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. 2022 Mar 18;13(4):8255–8265. doi: 10.1080/21655979.2022.2051686

Figure 4.

Figure 4.

miR-124-3p directly targets ARRDC1.

A: TargetScan 7.2 predicted the miR-124-3p binding sites in the 3’ UTR of ARRDC1. B: Luciferase assay showing the decrease in luciferase activity in cells co-transfected with miR-124-3p mimics and ARRDC1 3’ UTR WT. C: ARRDC1 mRNA level was significantly elevated in human HCC tissues. D: qRT-PCR showing that overexpression of miR-124-3p downregulated the expression of ARRDC1 at mRNA level. E: qRT-PCR showing that overexpression of miR-124-3p downregulated the expression of ARRDC1 at mRNA level. t-test; **P < 0.01 vs. control group.