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. 2022 Jun 4;76(9):5991. doi: 10.1007/s11696-022-02315-9

Retraction Note to: Discovery of (E)-N-(4-cyanobenzylidene)-6-fluoro-3-hydroxypyrazine-2-carboxamide (cyanorona-20): the first potent and specific anti-COVID-19 drug

Amgad M Rabie 1,
PMCID: PMC9166213  PMID: 35692492

Retraction Note to: Chemical Papers (2021) 75:4669–4685 10.1007/s11696-021-01640-9

The Editor-in-Chief has retracted this article. After publication, Dr Michal Šoral (Slovak Academy of Sciences) raised concerns with respect to the complete inconsistency of the NMR spectra presented in the Supplementary Information files with the assigned structure of the key compound cyanorona-20 ((E)-N(4-cyanobenzylidene)-6-fluoro-3-hydroxypyrazine-2-carboxamide) in this article. Independent post-publication peer review supported these concerns and verified that there is overlap of the NMR spectra with those in a previously published article (Rabie 2020). In addition, independent efforts to reproduce the synthesis of cyanorona-20 were unsuccessful. The Editor-in-Chief therefore no longer has confidence in the results and conclusions presented. The author does not agree with this retraction.

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Reference

  1. Rabie AM. Accurate conventional and microwave-assisted synthesis of galloyl hydrazide. MethodsX. 2020;7:100737. doi: 10.1016/j.mex.2019.11.010. [DOI] [PMC free article] [PubMed] [Google Scholar]

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