Biochemistry Retraction for “β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi,” by George S. Baillie, Arvind Sood, Ian McPhee, Irene Gall, Stephen J. Perry, Robert J. Lefkowitz, and Miles D. Houslay, which was first published January 27, 2003; 10.1073/pnas.262787199 (Proc. Natl. Acad. Sci. U.S.A. 100, 940–945).
The undersigned authors note the following, “We were informed by the University of Glasgow Research Integrity Council that, as part of a larger investigation of anomalies in a series of papers from one of their laboratories, it was found that lanes 2 and 3 of Fig. 4C are identical. While the data in this figure panel were obtained in myocardial cells, which are the sole focus of Fig. 4, the University of Glasgow did not identify irregularities in any other data presented in the paper, including the data obtained with HEK cells, which constitute the remainder of the data in the paper (Figs. 1–3). Nonetheless at the request of the University of Glasgow the paper is being retracted. We offer our apologies to the scientific community for any inconvenience this may have caused.”
George S. Baillie, Arvind Sood, Ian McPhee, Stephen J. Perry, and
Robert J. Lefkowitz