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. 2022 Jun 7;40(32):4424–4431. doi: 10.1016/j.vaccine.2022.05.090

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© 2022 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — IgG binding and spike neutralisation at 30–60 days following illness onset among participants with mild COVID-19 who did (N = 16) and did not (N = 36) develop PASC Difference in 30–60 day WT-D614G spike protein neutralising IgG titers and anti-spike and anti-RBD IgG binding titers between those who did and did not develop PASC with mild COVID-19. The mean effects on neutralising and IgG titers from those who did and did not develop PASC were estimated using a Bayesian multilevel model. Differences in posterior means were mean-centred such that effect sizes shown can be compared on a common scale (top row). Distributions of serum spike protein neutralising IgG titers (bottom left), spike binding (bottom middle) and RBD binding (bottom right) displayed such that each dot represents one participant. RBD = Receptor binding domain. PASC = Post-acute sequelae of COVID-19.