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Schematic diagram of AuNPs-PEI-pDNA complexes entering and expressing in cells
AuNPs-PEI-pDNA complex could attach around the cell through electrostatic adsorption and entered the cell wall through pores. Subsequently, it entered the cytoplasm through endocytosis of cell membrane, and further entered the nucleus. Owing to the proton sponge effect of PEI, AuNPs-PEI released pDNA they carried.
