Theme	Research questions	Probing questions
Background information	Can you start by telling me a bit about yourself and your job?	•How often do you see MS patients? •How long have you worked in the MS department? •Do you have managerial responsibility in your current position? •Do you work both clinical and with research? •How old are you?
Practice	Can you describe a typical consultation? How is data included in your work? How is the division of labor in the department?	•How long do you have per. patient – How much time do you spend with the patient – how much time do you use on preparation? •How do you prepare for a consultation – which patient “types” do you meet in your work? •What data/measures/samples do you use? •What do you use data for? •How much of your time is spent in front of the screen? •Are patients' health data shared – e.g., with physiotherapist or in relation to best practice/quality assurance •Is there a hierarchy associated with the work tasks
Values	Which values guide you in your work?	•What is the most important for you, in your work with MS-patients? •Is there anything else that is important or plays a role in your work? •How should the relationship between doctor and patient look like
PRO-data	What do you know about PRO? Do you have any experience with PRO? What are the advantages/disadvantage of PRO (what you think PRO is) – e.g., advantages/disadvantages of other PRO use What value can PRO provide What do you imagine PRO will mean for the current work procedure? Are there any patients who cannot contribute PRO data? What changes would it require to implement PRO as part of the treatment of MS patients What is your opinion on using PRO as a visitation tool?	•What do you think the purpose of PRO is? •How do you think PRO works? •Which information •In which connection •Do you ask your patients questions during the consultation? •What can PRO bring to your work •What are PROs strengths •Which factors are a barrier for the use of PRO in the treatment of MS patients? •What do you think about gaining insights from PRO about issues you can't help with right now – what are your options for directing your patient to another health care professional? •Is there a specific problem you think that PRO cannot solve? •Will PRO cause any changes in your tasks? •Will PRO entail any change in division of labor in the department? •Can all patients use PRO (why not)? •What changes will it require of you in your work •What changes will it require in the department •What changes will it require of the health system •For example. The patients fill in the questionnaire and is ranked according to green, yellow, and red witch determines whether they should go for a check-up (AMBUFLEX)
Data quality	What characterizes high quality data Can patients provide valid data	•Which data is most relevant to you/in your work? •Is there any data that is more useful than anything else? •Has subjective data value/data from the patient •How much can the patients influence data
Need	Is there any lack of relevant knowledge in your work? What should the PRO tool look like to be meaningful in your everyday life	•Is there anything special you need to know about your patients? •How should data be presented if you are to use it in your work (diagrams, color codes etc.) •How to obtain it (before/in consultation/control) •At what frequency should data be collected