Table 3.
Studies analyzed | k | Mean risk ratio | p-value | % above 1 | % above 1.1 | % above 1.2 | |
---|---|---|---|---|---|---|---|
Main analysis | 100 | 1.22 [1.13, 1.33] | <0.0001 | 0.12 | 83 [72, 91] | 71 [59, 80] | 53 [38, 64] |
Excluding borderline-eligible studies | 91 | 1.21 [1.11, 1.33] | 0.0003 | 0.12 | 82 [69, 91] | 68 [55, 77] | 52 [35, 63] |
Excluding composite interventions | 52 | 1.29 [1.18, 1.40] | <0.0001 | 0.11 | 98 [NA, NA] | 87 [71, 94] | 71 [38, 83] |
Studies at lowest risk of bias | 12 | 1.3 [0.98, 1.72] | 0.06 | 0.21 | 92 [NA, NA] | 75 [0, 92] | 58 [8, 83] |
Excluding studies measuring intended behavior | 43 | 1.11 [0.98, 1.26] | 0.08 | 0.14 | 70 [47, 88] | 47 [26, 60] | 30 [9, 49] |
Randomized studies | 75 | 1.24 [1.14, 1.34] | <0.0001 | 0.15 | 93 [79, 99] | 80 [66, 88] | 61 [36, 77] |
Preregistered studies with open data | 21 | 1.09 [0.99, 1.19] | 0.06 | 0 | 100 [NA, NA] | 0 [NA, NA] | 0 [NA, NA] |
Published studies | 17 | 1.35 [1.09, 1.67] | 0.02 | 0.16 | 100 [NA, NA] | 88 [NA, NA] | 71 [0, 94] |
Unpublished studies | 83 | 1.19 [1.08, 1.32] | 0.001 | 0.13 | 80 [65, 89] | 66 [52, 77] | 51 [34, 64] |
Excluding one extreme estimate | 99 | 1.22 [1.13, 1.33] | <0.0001 | 0.1 | 83 [71, 91] | 71 [59, 80] | 53 [36, 64] |
Including SSWS studies | 108 | 1.31 [1.19, 1.44] | <0.0001 | 0 | 81 [71, 87] | 69 [56, 76] | 56 [44, 65] |
p-value: for mean risk ratio versus null of 1. k: Number of studies in subset. : estimated standard deviation of true population effects on log-risk ratio scale. Final three columns: estimated percentage of true population effects stronger than various thresholds on risk ratio scale. Bracketed values are 95% confidence intervals for the percentage of effects stronger than a threshold, which were sometimes not estimable (“NA”) when exactly or when the estimated proportion was very high.