Table 1.
Patient Characteristics
| Type 1 VWD | Type 2 VWD | Type 3 VWD | Total | |
|---|---|---|---|---|
| n = 252 | n = 124 | n = 14 | n = 390 | |
| Age, mean ± SD | 44 ± 18 | 42 ± 19 | 29 ± 22 | 43 ± 19 |
| Female, n (%) | 167 (66.3) | 76 (61.3) | 7 (50.0) | 250 (64.1) |
| Blood group O, n (%) | 169 (68.4) | 67 (54.5) | 6 (42.9) | 242 (63.0) |
| Variant found, n (%) | 155 (61.5) | 122 (98.4) | 14 (100) | 291 (74.6) |
| Families, n | 226 | 94 | 13 | 326a |
| VWF:Ag | 0.38 (0.25–0.55) | 0.25 (0.16–0.37) | 0.00 (0.00–0.03) | 0.31 (0.19–0.48) |
| VWF:Ab | 0.48 (0.24–0.74) | 0.08 (0.03–0.18) | 0.00 (0.00–0.00) | 0.29 (0.11–0.60) |
| VWF:CB | 0.45 (0.24–0.69) | 0.08 (0.06–0.23) | 0.00 (0.00–0.02) | 0.29 (0.10–0.56) |
| FVIII:C | 0.68 (0.51–0.90) | 0.37 (0.25–0.50) | 0.01 (0.01–0.04) | 0.56 (0.36–0.78) |
| Bleeding score | 9 (6–15) | 11 (7–17) | 20 (13–25) | 10 (6–16) |
Data are presented as median (interquartile ranges), unless otherwise specified.
aSome relatives had different types of VWD; therefore, the sum of number of families per type is more than 326.
VWD = von Willebrand disease.