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. 2022 Jun 16;185(16):2952–2960.e10. doi: 10.1016/j.cell.2022.06.023

Figure 3.

Figure 3

The G496S mutation in RBD and N90-glycan in hACE2 modulate the RBDs/hACE2 interaction

(A) The G496S mutation affects the local polar interaction networks at the RBD/hACE2 interfaces.

(B) The interaction between hACE2 N90-glycan may be related to the R408S mutations in the BA.2 RBD/hACE2 complex. The four panels from the leftmost one in (A) and (B) are BA.1 RBD/hACE2 (PDB: 7WBP), BA.1.1 RBD/hACE2, BA.2 RBD/hACE2, and BA.3 RBD/hACE2, correspondingly. The numbers on the dash lines are distances (Å) between the two atoms they link.

See also Figures S3–S6.