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. 2022 Jun 13;10(6):1395. doi: 10.3390/biomedicines10061395

Correction: Karakus et al. Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult. Biomedicines 2021, 9, 1713

Ozlem Ozen Karakus 1, Noureldien H E Darwish 1,2, Thangirala Sudha 1, Taher A Salaheldin 1, Kazutoshi Fujioka 1, Peter C Taylor Dickinson 3, Brian Weil 4,5, Shaker A Mousa 1,*
PMCID: PMC9220413  PMID: 35740483

In the published manuscript [1] in the Results section, in the subsection titled 3.5. Cardioprotective Effects of T3 and PLGA-T3/PCr NPs under Hypoxia, in Figure 6A there was an unintentional mistake of an overlap in Figures under different treatment conditions while taking photographs/labeling at a lower magnification. Experiment was repeated and photographs were taken under higher magnification for improved image quality. The scientific conclusion was unaffected and there is no change in the legend of the figure. The published figure is replaced with the new Figure 6A.

Figure 6.

Figure 6

Expression of troponin T in neonatal cardiomyocytes under hypoxic condition. (A) Immunostaining by anti-troponin T-PE (confocal microscopy). (B) Quantitation of troponin T in neonatal cardiomyocyte and in medium. ** p < 0.05, *** p < 0.001 versus untreated control, with full reversal and improvement versus control under normoxic condition. These results suggest that PLGA-T3 NPs and PLGA-T3 NPs/PCr inhibit the damaging effect of hypoxia on cardiomyocytes.

The authors apologize for any inconvenience. This correction was approved by the Academic Editor. The original publication has also been updated.

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Reference

  • 1.Karakus O.O., Darwish N.H.E., Sudha T., Salaheldin T.A., Fujioka K., Dickinson P.C.T., Weil B., Mousa S.A. Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult. Biomedicines. 2021;9:1713. doi: 10.3390/biomedicines9111713. [DOI] [PMC free article] [PubMed] [Google Scholar]

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