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Schematic illustration of some major steps, metabolites, and substrates involved in the kynurenine pathway (KP). IDO—indoleamine 2,3-dioxygenase; TDO—tryptophan 2,3-dioxygenase; KAT—kynurenine aminotransferase; KMO—kynurenine-3-monooxygenase; 3HAO—3-hydroxyanthranilic acid dioxygenase; KYNU—kynureninase.
