Article title: Screening Tests: A Review With Examples
Authors: Maxim, D., Niebo, R., & Utell, M.
Journal: Inhalation Toxicology
Bibliometrics: Volume 26, Number 13, pages 811–828
DOI: http://dx.doi.org/10.3109/08958378.2014.955932
From the Authors: In response to the comments of Dr. McKee, we concur that there is an error in Table 5. Dr. McKee correctly points out that “False Positive Rate” was incorrectly identified and should have been “False Discovery Rate” as shown in the corrected table below. In relation to this table, each of the the instances related to Table 5 where we say “false positive rate”, we should have said “false discovery rate”. We would point out that in Table 4, “false positive rate” is correctly defined. We appreciate Dr. McKee bringing this error to our attention.
Table 5.
Reported false discovery rates for CT scans for lung cancer.
| Reported false | ||
|---|---|---|
| discovery rates as % | Remarks | Source |
| 96.4 | NationalLungScreeningTrialResearchTeam,p.399 | NationalLungScreeningTrial |
| ResearchTeam( 2011) | ||
| 96.1 | Studyalsoreports90%sensitivity | Swensenetal.(2003) |
| 95.5 | 106falsepositivesamong111withnodules >0.5cm | Tiitolaetal.(2002) |
| 92.9–96.0 | Ratesdependedonnodulesize,p.260. | Swensenetal.(2005) |
| 86.6–96.4 | Ratesdependuponassumednodulesizefrom5.0to9.0mm | Henschkeetal.(2013) |
| 94.6 | Basedon14detectedcancersamong259patientswithabnormalCTscans | McWilliamsetal.(2003) |
| 94.1 | FromTable2,1773falsepositivesamong1883nodulesdetected | Mahadeviaetal.(2003) |
| 93 | Basedon8lungcancersamong114subjectswithnodules >5mm | Novelloetal.(2005) |
| 92.6 | Basedon22lungcancersamong298patientswithnodules | Pastorinoetal.(2003) |
| 92.1 | Basedon22cancersin279withsuspiciousnodules | Soneetal.(2001) |
| 88.5–97 | FromTable3,ratedependentuponrisk | Kovalchiketal.(2013) |
| 87.6 | Basedon29malignanciesamong233positiveresults | Henschkeetal.(2002) |
| 75 | Percentofpatientswithnon-calcifiednodulesonCT | Manos(2013) |
| 73.4 | Basedon163benignnodulesamong222evaluatedbythinsectionCT | Lietal.(2004) |
| >70 | ReportedvaluederivedfromMayoclinicandELCAPtrials | Patzetal.(2004) |
| 62.1 | Basedon18falsepositivesamong29subjects;fornodules >10mm | Diedrerichetal.(2002) |
| 43.75 | Basedon36confirmedlungcancercasesamong64patients | Nawaetal.(2002) |
| 21–33 | Ratesdependuponnumberoftests,p.509.Ofparticipantswithafalse-positiveCTscan,7% | Croswell et al. (2010) |
| hadanunnecessaryinvasiveprocedureand2%hadmajorsurgeryforbenigndisease. | ||
| 19 | p.119 | Gohaganetal.(2004) |
| 7.9 | p.612.Includesmulti-stageprocesswithclassificationofnodulesbysizeand | Pedersenetal.(2009), |
| calcification withfollow-up. | Saghiretal.(2012) | |
| 7.9M/5.6F | Sensitivityreportedtorangebetween84.6%Wto90.6%M | Toyodaetal.(2008) |
| 1.7 | Sensitivityreportedat94.6%,basedonVolumeCTscanning | vanKlaverenetal.(2009) |
Mark Utell, MD
L. Daniel Maxim, PhD (Deceased)