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. Author manuscript; available in PMC: 2022 Jun 30.
Published in final edited form as: Pain. 2020 Oct;161(10):2330–2343. doi: 10.1097/j.pain.0000000000001926

Table 3.

The results of KEGG pathway analysis for the DEGs in the nociceptive trait comparison.

KEGG pathway ID Pathway N DE P
 hsa04151 PI3K-Akt signaling pathway 199 45 0.00799
 hsa04360 Axon guidance 118 37 2.06E-05
 hsa04510 Focal adhesion 137 32 0.01443
 hsa04931 Insulin resistance 79 25 0.00037
 hsa04380 Osteoclast differentiation 76 20 0.01366
 hsa04625 C-type lectin receptor signaling pathway 72 19 0.01551
 hsa04670 Leukocyte transendothelial migration 72 18 0.03074
 hsa01524 Platinum drug resistance 60 16 0.02277
 hsa04660 T cell receptor signaling pathway 64 16 0.04013
 hsa04146 Peroxisome 65 16 0.04565
 hsa05100 Bacterial invasion of epithelial cells 65 16 0.04565
 hsa03430 Mismatch repair 21 7 0.03841
 hsa04710 Circadian rhythm 22 7 0.04884

The “N” column denotes the total number of genes in each pathway. The “DE” column denotes the number of genes in the pathway identified as significantly expressed in the nociceptive trait. The “P.DE” column lists the P-value statistic of the genes found in each pathway. Significant (P.DE < 0.05) pathways are listed.

KEGG, Kyoto Encyclopedia of Genes and Genome.