Skip to main content
. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Nature. 2022 Jun 15;606(7916):960–967. doi: 10.1038/s41586-022-04825-8

Extended Data Figure 11. Caspase-7 enhances ceramide production via ASM after NK/CTL attack.

Extended Data Figure 11.

a-c, Mice were treated with imipramine or PBS, followed by intraperitoneal infection with 104 C. violaceum and harvested 3 dpi. Representative images of infected livers from WT (a), Casp7−/− (b), or WT+IMP (c) mice stained for nuclei (DAPI; blue), cleaved caspase-7 (white), and ceramide (red). Scale bars, 50 μm. Data are representative of 3 experiments.