Figure 4.
VTP and PD-1/PD-L1 blockade synergize to reject orthotopic renal tumors and prolong survival. On the 21st day, renal tumor growth was evaluated by renal weight (A) and maximum cross-sectional tumor area (B); (C) The kidneys were collected on the 21st day and stained with H&E. PD-L1 expression induced by VTP in (D) A-498 tumors and (E) 786-O tumors in the flanks of nude mice; (F) The ratio of PD-L1 positive cells in Amur498 tumor and 786muro tumor was evaluated. Adapted with permission from 43, copyright 2018 American Association for Cancer Research.