Table 1.
Patient characteristics in the four molecular clusters.
| Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | |
|---|---|---|---|---|
| Patient number | n=29 | n=20 | n=16 | n=17 |
| Early-onset cases | 7 (24%) | 3 (15%) | 0 (0%) | 1 (6%) |
| Late-onset cases | 22 (76%) | 17 (85%) | 16 (100%) | 16 (94%) |
| BW percentile* | 79% | 89% | 100% | 86% |
| SGA cases | 9 (31%) | 3 (15%) | 2 (15%) | 3 (18%) |
| Nulliparity | 22 (76%) | 13 (65%) | 11 (69%) | 14 (82%) |
| Diabetes | 7% | 15% | 13% | 6% |
| BMI | 26 | 29 | 30 | 25 |
| Chr. hypertension | 28% | 25% | 31% | 6% |
| History of PE | 7% | 0% | 19% | 0% |
| Smoking | 7% | 10% | 0% | 18% |
| PIGF* | 66% | 90% | 90% | 103% |
| PAPP-A* | 59% | 72% | 62% | 81% |
| Mean Doppler PI* | 116% | 109% | 109% | 112% |
| First trim. MAP* | 113% | 118% | 116% | 109% |
Bold, colored numbers indicate statistically significant difference from controls. Asterisks denote percentage of control mean. BMI, body mass index. BW, birthweight; MAP, mean arterial pressure; PE, preeclampsia; PI, pulsatility index; PAPP-A, pregnancy-associated plasma protein A; PlGF, placental growth factor; SGA, small for gestational age.