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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: AIDS. 2022 Apr 19;36(8):1117–1127. doi: 10.1097/QAD.0000000000003229

Figure 4. Association of demographic and HIV disease characteristics with changes in biomarker levels from Tc to Te.

Figure 4.

Changes were defined by the differences in biomarker concentrations from Tc to Te. Effect sizes greater than 1.0 indicate a lesser relative decline (or greater relative increase) in biomarker concentrations between Tc (initiation of controlled viremia) and Te (entry in P1104s) when follow up sample was collected, on average, in the comparison group relative to the referent group. Separate multivariable models were fit for each biomarker. The following covariates were included in each model: sex, age, antiretroviral regimen and biomarker concentration at Tc; nadir CD4%, height WHO Z score and weight WHO Z score; peak plasma HIV RNA copies/ml; and duration of controlled viremia from Tc to Te. Dark boxes indicate associations with p<0.05.