Figure 2.

DNA-PKcs deficient CHO mutants uniformly show increased resection in G₂-phase. (A) Western blot of DNA-PKcs in human 82-6 hTert and hamster CHOK1 cells. (B) As in Figure 1B for CHOK1 (wt) and the DNA-PKcs mutants, XR-C1-3, V3 and irs20. (C) As in Figure 1C for the mutants in panel (B). (D) As in Figure 1D for the mutants in panel (B). (E) As in panel (C) for data obtained using FC with the same mutants. * indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001, while n.s. indicates non-significance.