Table 1.

Comparison of the effect of iron replacement (IR) and drug on motor activity in the striatal-lesioned iron deficient rats¹.

	WT	ID-STL
		B	IR4	TP	PR
ILMSI	20.5 ± 5.5	19.7 ± 2.56	18.1 ± 2.9	18.6 ± 4.4	21.9 ± 0.9
PLMSI	6.1 ± 2.8	35.5 ± 6.79a	24.3 ± 4.5b,d	4 ± 1.6e	12.4 ± 0.7c,f,h
PLMWI	0	11.6 ± 5.05a	12.7 ± 10.7b	0.8 ± 1.1e,g	7.5 ± 7.3

¹Data (mean ± SD) taken from 8 hour recording after drug injection. B: baseline, ID-STL: striatal-lesioned iron-deficient rat, ILMSI: index of isolated leg movements in sleep, IR4: iron deficient rats fed with standard rodent diet for 4 weeks, PLMSI and PLMWI: index of periodic leg movements (PLM) in sleep (PLMS) and in quiet wake (PLMW), respectively, PR: pramipexole, TP: thioperamide. WT: wild-type rat.

^aSignificant difference between WT and ID-STL-B rats.

^bSignificant difference between WT and ID-STL-IR4 rats.

^cSignificant difference between WT and ID-STL-PR (pramipexole injection) rats.

^dSignificant difference between ID-STL-B and ID-STL-IR4 rats.

^eSignificant difference between ID-STL-B and ID-STL-TP (thioperamide injection) rats.

^fSignificant difference between ID-STL-B and ID-STL-PR rats.

^gSignificant difference between ID-STL-IR4 and ID-STL-TP rats.

^hSignificant difference between ID-STL-IR4 and ID-STL-PR rats.