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. 2022 Jun 15;13(5):13815–13828. doi: 10.1080/21655979.2022.2084460

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Overexpression of hsa_circ_0057452 facilitates the survival and migration of KFs, and inhibits their apoptosis. (a) The overexpressed efficiency of hsa_circ_0057452 was evaluated by qRT-PCR in KFs transfected with OE-NC and OE-circ, respectively. (b) CCK-8 assays were performed to assess the viability in KFs transfected with the OE-NC and OE-circ, respectively. (c) BrdU assays were performed to assess the proliferation ability in KFs transfected with the OE-NC and OE-circ, respectively. (d) Cell apoptosis was examined using flow cytometry in KFs transfected with the OE-NC and OE-circ, respectively. (e) Transwell migration assays were applied for assessing the migration ability of KFs transfected with the OE-NC and OE-circ, respectively. **P < 0.001 vs. OE-NC.