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. 2022 May 29;13(5):13150–13161. doi: 10.1080/21655979.2022.2070582

Figure 4.

Figure 4.

CircTEX14 promoted THAP1 expression by targeting miR-6509-3p. (a) The binding sites of miR-6509-3p and THAP1. (b) The luciferase activities in VSMCs co-transfected with miR-6509-3p and THAP1-WT or THAP1-MT. (c) THAP1 mRNA expression in VSMCs co-transfected with miR-6509-3p or miR-NC, and circTEX14 or control. (d) THAP1 protein expression in VSMCs co-transfected with miR-6509-3p mimics or miR-NC, and circTEX14 vector or control vector. (e) THAP1 mRNA expression in serum of atherosclerosis patients and healthy volunteers. (f and g) Pearson’s correlation of miR-6509-3p, circTEX14, and THAP1 in serum of atherosclerosis patients. * vs. control, # vs. miR-6509-3p. **p < 0.01 vs. miR-NC, ## p < 0.01.