Lauren E Fritsch
Lauren E Fritsch
1Translational Biology, Medicine, and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, VA, United States
1,
Jing Ju
Jing Ju
2Molecular and Cellular Biology Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
2,
Erwin Kristobal Gudenschwager Basso
Erwin Kristobal Gudenschwager Basso
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Eman Soliman
Eman Soliman
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Swagatika Paul
Swagatika Paul
4Biomedical and Veterinary Sciences Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
4,
Jiang Chen
Jiang Chen
2Molecular and Cellular Biology Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
2,†,
Alexandra M Kaloss
Alexandra M Kaloss
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Elizabeth A Kowalski
Elizabeth A Kowalski
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Taylor C Tuhy
Taylor C Tuhy
5School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
5,
Rachana Deven Somaiya
Rachana Deven Somaiya
1Translational Biology, Medicine, and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, VA, United States
1,
Xia Wang
Xia Wang
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Irving Coy Allen
Irving Coy Allen
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,
Michelle H Theus
Michelle H Theus
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
5School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3,5,*,
Alicia M Pickrell
Alicia M Pickrell
5School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
5,*
1Translational Biology, Medicine, and Health Graduate Program, Virginia Polytechnic Institute and State University, Roanoke, VA, United States
2Molecular and Cellular Biology Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
3Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
4Biomedical and Veterinary Sciences Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
5School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States
Edited and reviewed by: Andrei Surguchov, University of Kansas Medical Center, United States
✉*Correspondence: Alicia M. Pickrell alicia.pickrell@vt.edu
*Michelle H. Theus mtheus@vt.edu
This article was submitted to Brain Disease Mechanisms, a section of the journal Frontiers in Molecular Neuroscience
†Present address: Jiang Chen, Sorrento Therapeutics, Inc., San Diego, CA, United States
Received 2022 Jun 9; Accepted 2022 Jun 10; Collection date 2022.
Keywords: brain injury, inflammation, STING, cGAS, innate immunity
Copyright © 2022 Fritsch, Ju, Basso, Soliman, Paul, Chen, Kaloss, Kowalski, Tuhy, Somaiya, Wang, Allen, Theus and Pickrell.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.