Abstract
In April 2021, we assessed mRNA vaccine effectiveness (VE) in the context of a COVID-19 outbreak in a skilled nursing facility. Among 28 cases, genomic sequencing was performed on four specimens on four different patients, and all were classified by sequence analysis as the Beta (B.1.351) variant. Adjusted VE among residents was 65% (95% Confidence Interval: 25-84%). These findings underscore the importance of vaccination for prevention of COVID-19 in skilled nursing facilities.
Keywords: Vaccine Effectiveness, SARS-CoV-2, skilled nursing facility
Contributor Information
Heidi L Moline, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA.
Amelia Keaton, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Whitney Rice, Virginia Beach Health Department, Virginia Beach, VA.
Jasmine Varghese, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Li Deng, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Ansley Waters, Council of State and Territorial Epidemiologists; Virginia Department of Health, Richmond, VA.
Anna Barringer, Virginia Beach Health Department, Virginia Beach, VA.
Devonne Winston, Virginia Beach Health Department, Virginia Beach, VA.
Virgie Fields, Virginia Department of Health, Richmond, VA.
Kara Jacobs Slifka, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Jennifer R Verani, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Stephanie J Schrag, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
John Jernigan, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Jacqueline E Tate, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
Katherine E Fleming-Dutra, COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA.
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