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. 2022 May 27;65(8):1315–1327. doi: 10.1007/s00125-022-05703-8

Table 1.

Description of the research population

Primary study (children with type 1 diabetes) Primary with measured islet autoantibodiesa Follow-up family-based study
Variable Very young Pre-pubertal Pubertal Post-pubertal 1 2 3 4 Healthy siblings Type 1 diabetes
Number of participants 391 918 550 58 13 34 72 181 244 188
Number of female participants 192 352 312 48 8 14 28 86 116 86
Age of female participants (years) 4.2 (0.6–6) 8.8 (6–11) 12.6 (11–15) 16 (15–19.1) 12.7 (6.9–14.5) 10.7 (2.3–14.4) 9.2 (4.7–14.9) 9.7 (0.6–16.1) 11 (2–23) 9.7 (0.6–16.1)
Number of male participants 199 566 238 10 5 20 44 95 128 102
Age of male participants (years) 4 (0.6–6) 10.3 (6–13) 14.3 (13–16.9) 17.4 (17–18.3) 10.2 (5.4–11.8) 11.4 (2–15.9) 11.5 (2.4–17.6) 10.7 (2.6–16.1) 11 (2–23) 10.1 (1.4–16.9)

Values for age are medians (range)

aGrouped by number of autoantibodies