FIGURE 10.

FA In SLFp and SLFt predict MPH effects on β depression in the ADHD group. (a) Bar plot shows beta regression coefficients associated with mdl(4), where mean FA values along the tracts of interest are defined as predictors for changes in beta modulation due to medication intake (ΔPI(β)). According to equation (2), a higher ΔPI (β) value for a given ADHD subject reflects bigger changes in depression of beta oscillations following medication intake. (b) Adjusted response plot showing ΔPI (β) as a function of FASLFt. A significant beta coefficient (p = .001) reveals that FASLFt predicted lower changes in β power depression due to MPH. (c) Adjusted response plot showing ΔPI(β) as a function of FASLFp. Higher FASLFp corresponded to stronger β depression changes following MPH intake (p = 1 × 10–4). (d) Adjusted response plot illustrating ΔPI (β) as a function of parietotemporal SLF gradient according to mdl(4.a). Higher SLF (p–t), for a given ADHD subject, reflected higher diffusivity at parietal endings, as compared to temporal endings, of the SLF. The significant positive relationship (p = 7 × 10–4) suggests that the gradient of parietotemporal diffusivity in the SLF is predictive of the effects of MPH on β depression