Comparison of the mean level of lactate dehydrogenase for the experimental groups compared to the negative control group. A: negative control group with 2 mL of distilled water gavage, Group B: mg/kg b.w of PQ by gavage, once daily for three days, Group C: 60 mg/kg b.w of PQ by gavage, once daily for three days, Group D: 200 mg/kg b.w of PQ once by gavage, Group E: 50 mg/kg b.w PQ for three weeks, twice a week by gavage (total 6 times) (∗(P<0.05)).