Fig. 4.

CTB-ACE2 chewing gum trapping efficacy assessed through diagnosis with RAPID. Normalized charge-transfer resistance values for the electrochemical impedance spectroscopy measurements of 20 SARS-CoV-2 clinical samples (left y-axis) before and after exposure to 20 mg of ACE2 chewing gum. RNA copies μL ⁻¹ from qPCR of infected samples prior to exposure to the ACE2 chewing gum (right y-axis). Numbers below samples are patient IDs. Please refer to Table 1 for other details. Sample ID 593 was not genotyped. Samples 595–609 are Delta and 613–631 are Omicron SARS-CoV-2 strain identification is based on whole genome sequencing or S gene target failure or date of collection. RNA extraction was from 140 μL patient sample (1/50 μL shown) and RAPID was performed in 100 μL patient sample (10 μL Rct value shown).