Abstract
We experienced a patient with Legionella pneumonia developing immediately after discharge from COVID‐19 recovery. Antibiotic treatment was successful. The source of Legiolella infection was proven to be bathtub water in this case. It is very important to accurately detect pathogens, particularly in the time of pandemics such as COVID‐19.
Keywords: COVID‐19, Legionella pneumonia, Legionella pneumophila, SARS‐CoV‐2, serogroup 5
Identification of the causative organism is extremely important in infectious disease. A subsequent infectious disease such as pneumonia immediately after recovery from COVID‐19 may pose a pitfall; legionellosis can be an important life‐threatening infectious disease. Patients should be carefully followed up after discharge.
1. CLINICAL IMAGE
An 83‐year‐old woman visited our emergency department with consciousness disorder, high fever, and hypoxemia 5 days after healing and discharge from COVID‐19. Examination data on Day 1 revealed high inflammatory responses. Chest X‐ray and CT (Figure 1A) revealed features of severe pneumonia which are obviously distinct from those at COVID‐19. The SARS‐CoV‐2 antigen was negative, but urinary Legionella antigen was positive, and Legionella pneumophila serogroup 5 was detected from her sputum. Legionella pneumonia was diagnosed. Levofloxacin was effective for the Legionella pneumonia, but secondary bacterial pneumonia developed; other antibiotic therapy was successful. She was transferred to a long‐term hospital on Day 68 (Figure 1B). Legionella pneumophila was detected in her daily reused bathtub water (Figure 2); this very common Japanese lifestyle in Japan can be a hotbed of Legionella infection. Increasing focus on Legionnaires' disease is needed in association with relaxation of lockdown as the COVID‐19 pandemic recedes. 1 Legionellosis after influenza is reported, 2 but this is the first case of Legionella pneumonia after COVID‐19 infection. Patients should be followed up for subsequent infections after discharge.
FIGURE 1.
Clinical course of patient with images. (A) Images of plain X‐ray and CT scan on indicated date with percutaneous oxygen saturation (SpO2), CRP, and body temperature (BT). (B) Clinical course of CRP with treatments. This patient was hospitalized with COVID‐19 between Day −14 and Day −5, then, re‐hospitalized on Day 1 with Legionnaire's disease. DEX, dexamethasone; LVFX, levofloxacin; TAZ/PIPC, tazobactam/piperacillin; MEPM, meropenem.
FIGURE 2.
(A) Bathtub filled with reused water in this patient's home. (B) Gimenez staining disclosed Legionella pneumophila in both patient's sputum and bathtub water. Staining results from bathtub water are shown.
AUTHOR CONTRIBUTIONS
DJ, HT, SU, and HW substantially contributed to the diagnosis and clinical care of the patient. DJ wrote the draft of the manuscript, and DJ and AH critically revised it for important intellectual content.
FUNDING INFORMATION
None.
CONFLICT OF INTEREST
None declared.
CONSENT
Written informed consent was obtained from the patient to publish this report in accordance with the journal's patient consent policy, and the study was approved by the Ethics Committee in Saka General Hospital (No. 21–9‐21).
ACKNOWLEDGEMENT
We are grateful to Barbara Lee Smith Pierce (Retired Professor, University of Maryland University College) for her editorial work in the preparation of the manuscript.
Jingu D, Takahashi H, Ubukata S, Watanabe H, Horii A. Legionella pneumonia immediately after recovery from COVID‐19. Clin Case Rep. 2022;10:e06090. doi: 10.1002/ccr3.6090
DATA AVAILABILITY STATEMENT
No data are available in this case report.
REFERENCES
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Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Data Availability Statement
No data are available in this case report.