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. Author manuscript; available in PMC: 2022 Jul 21.
Published in final edited form as: Mol Cancer Res. 2022 Jul 6;20(7):1179. doi: 10.1158/1541-7786.MCR-22-0454

Retraction: αB-Crystallin, an Effector of Unfolded Protein Response, Confers Anti-VEGF Resistance to Breast Cancer via Maintenance of Intracrine VEGF in Endothelial Cells

Qing Ruan, Song Han, Wen G Jiang, Michael E Boulton, Zhi J Chen, Brian K Law, Jun Cai
PMCID: PMC9302381  NIHMSID: NIHMS1824539  PMID: 35791691

This article (1) has been retracted at the request of the editors. Following an institutional review by the University of Florida, the primary affiliation for several of the authors, it was determined that an image in this article was reused from an earlier Journal of Biological Chemistry study (2). Specifically, the last four bands in the blot labeled “α-Tubulin” in Fig. 1A of this article (1) were originally published as the middle four bands of the blot labeled “α-Tubulin” in Fig. 2D of the Journal of Biological Chemistry article (2). As a result of this and other findings from its investigation, the institution recommended retraction of this article (1), and, upon internal review, the editors agreed with this recommendation.

A copy of this Retraction Notice was sent to the last known e-mail addresses for all seven authors. Three authors (Song Han, Michael E. Boulton, and Brian K. Law) agreed to the retraction; two authors (Wen G. Jiang and Jun Cai) did not respond; and the two remaining authors (Qing Ruan and Zhi J. Chen) could not be located.

References

  • 1.Ruan Q, Han S, Jiang WG, Boulton ME, Chen ZJ, Law BK, et al. αB-Crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Mol Cancer Res 2011;9:1632–43. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  • 2.Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem 2006;281: 3604–13. [DOI] [PubMed] [Google Scholar]

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