The risk of acute liver injury (ALI) after COVID-19 vaccination (either the mRNA vaccine BNT162b2 or inactivated vaccine CoronaVac) was assessed in a case series analysis in Hong Kong of >2.3 million recipients of a COVID-19 vaccine who were at risk. The incidence of ALI after COVID-19 vaccination was very low and not increased compared with the non-exposure period; the majority of post-vaccination ALI was mild and self-limiting. The authors concluded that the potential benefits of mass vaccination for COVID-19 outweigh the risks of ALI from vaccination and SARS-CoV-2 infection.
References
Original article
- Wong CKH, et al. Risk of acute liver injury following the mRNA (BNT162b2) and inactivated (CoronaVac) COVID-19 vaccines. J. Hepatol. 2022 doi: 10.1016/j.jhep.2022.06.032. [DOI] [PMC free article] [PubMed] [Google Scholar]