Table 1.
Baseline population characteristics according to AMD status in the Alienor Study (n = 861, 2001–2017).
| Participants, No (%) | ||||
|---|---|---|---|---|
| Characteristics | Total (n = 861) | Incident AMD Cases (n = 93) | Non-Incident AMD Cases (n = 768) | p-Value a |
| Female, sex | 530 (61.6) | 68 (73.1) | 462 (60.2) | 0.02 |
| Age, mean (SD), y | 74.7 (4.3) | 76.4 (4.5) | 74.5 (4.2) | <0.001 |
| Smoking status, pack years | 0.61 | |||
| Never smoker | 549 (64.4) | 59 (64.1) | 490 (64.5) | |
| <20 | 153 (18.0) | 14 (15.2) | 139 (18.3) | |
| ≥20 | 150 (17.6) | 19 (20.7) | 131 (17.2) | |
| Missing data | 9 | 1 | 8 | |
| Physical activity | 0.28 | |||
| None | 459 (53.3) | 48 (51.6) | 411 (53.5) | |
| Medium | 173 (20.1) | 18 (19.4) | 155 (20.2) | |
| High | 87 (10.1) | 6 (6.5) | 81 (10.5) | |
| No answer | 142 (16.5) | 21 (22.5) | 121 (15.8) | |
| Alcohol consumption, mean (SD), g/day | 12.0 (14.5) | 12.0 (14.3) | 12.0 (14.5) | 0.98 |
| Missing data | 10 | 2 | 8 | |
| Use of AMD supplement | 98 (11.4) | 27 (27.5) | 71 (8.5) | <0.001 |
| Body mass index, mean (SD), kg/m2 | 26.4 (3.9) | 25.8 (3.6) | 26.4 (4.0) | 0.18 |
| Missing data | 5 | 0 | 5 | |
| HDL-Cholesterol, mean (SD), mg/dL | 61.9 (15.6) | 65.8 (16.0) | 61.5 (15.2) | 0.01 |
| Missing data | 46 | 5 | 41 | |
| Genetic risk score, mean (SD) | 0.28 (1.19) | 0.98 (1.35) | 0.19 (1.14) | <0.001 |
| Missing data | 141 | 12 | 129 | |
Abbreviations: AMD, age-related macular degeneration; CI, confidence interval; HDL, high-density lipoprotein; HR, hazard ratio; SD, standard deviation. SI conversion factors: To convert HDL-cholesterol to mmol/L, multiply by 0.0259; a p value were obtained by using Chi2 analyses for categorical data and t test for continuous variables.