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. 2022 Jul 14;27(14):4498. doi: 10.3390/molecules27144498

Figure 1.

Figure 1

The effect of CD26 inhibitors performed therapeutically in different immune-mediated diseases through a biased Th1 to Th2 cytokine profile. The inhibition of CD26 breaks Th1-cell-mediated immune stimulation, as well as activating the Th2-cell-mediated immune suppression.