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PGC-1α promoter activity is repressed by NF-κB. (A,B) Luciferase reporter assay of the mouse PGC-1α promoter in (A) NIH 3T3 cells or (B) rat post-natal cardiac myocytes transduced with empty vector alone (Control) or NF-κB p65 expression cassette, with normalization to co-transfected Renilla luciferase. * p < 0.05 versus Control.
