Table 1. Characterization of animal groups in the protective efficacy assay.

n of group	n of animals	Infection dose	Preparation dose	Time of injection preparation
1	12	101 median tissue culture infectious dose in 100 μl intranasal	1.0 ml anti-COVID-19 hyperimmune immunoglobulin	24 h before infection
2	12			2 h after infection
3	12			48 h after infection
4	12		1.0 ml normal intravenous immunoglobulin	24 h before infection
5	12		1.0 ml placebo	2 h after infection