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Neurogenesis and trophic factors. Neural stem cells generate progenitor cells. Trophic factors (bFGF and EGF) are necessary for the survival and proliferation of neural progenitor cells, while neurotrophin NGF promotes neuronal differentiation. Neural progenitors can give rise to the three principal phenotypes of the CNS: Neurons, Astrocytes, and Oligodendrocytes. “Created with BioRender.com (accessed on 1 May 2022)”.
