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. 2022 Jul 25;11(15):2294. doi: 10.3390/cells11152294

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Manipulating miR-31 regulates radiosensitivity in PDAC cell lines. (A) Overexpressing miR-31 in BxPC-3 cells significantly reduced surviving fraction (** p = 0.00891) post-irradiation. (B) Suppressing miR-31 in Panc-1 cells showed a significant increase in survival fraction (* p = 0.0211). All cells were irradiated with 4 Gy, while controls were mock-irradiated (0 Gy) 24 h post-seeding. Data are expressed as the mean ± SEM and analyzed by a two-tailed paired t-test (n = 3).

Manipulating miR-31 regulates radiosensitivity in PDAC cell lines. (A) Overexpressing miR-31 in BxPC-3 cells significantly reduced surviving fraction (** p = 0.00891) post-irradiation. (B) Suppressing miR-31 in Panc-1 cells showed a significant increase in survival fraction (* p = 0.0211). All cells were irradiated with 4 Gy, while controls were mock-irradiated (0 Gy) 24 h post-seeding. Data are expressed as the mean ± SEM and analyzed by a two-tailed paired t-test (n = 3).