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. 2022 Jul 26;12(8):1029. doi: 10.3390/biom12081029

Table 1.

Gene expression of contractile associated proteins and calcium ion channel in the myometrium. The gene expression levels of CAPs (oxytocin receptor, connexin 43, and PGF2α) and L-type calcium (Ca2+) channel in the myometrium were determined using real-time RT-PCR in each group (control, Porphyromonas gingivalis (P.g.) and P.g. + progesterone (P4)). Experiments were performed in duplicate using eight tissue samples. Statistical analysis was performed using the Mann–Whitney U test. Statistical significance was set at *: p < 0.05, compared P.g. with the control or: : p < 0.05, P.g. + P4 with P.g., respectively. Values represent the mean  ±  SD (n  = 8).

Control P.g. P.g. + P4
Oxytocin receptor 0.33 ± 0.30 1.10 ± 0.56 * 0.34 ± 0.14
Connexin 43 0.34 ± 0.19 1.11 ± 0.50 * 0.44 ± 0.18
PGF2α 0.25 ± 0.09 0.61 ± 0.11 * 0.45 ± 0.15
L type Ca2+ channel 1.39 ± 0.32 3.79 ± 1.77 * 1.16 ± 0.37

* p < 0.05 (comparison of P.g. with control), p < 0.05 (comparison of P.g. + P4 with P.g.).