Table 1.
Gene expression of contractile associated proteins and calcium ion channel in the myometrium. The gene expression levels of CAPs (oxytocin receptor, connexin 43, and PGF2α) and L-type calcium (Ca2+) channel in the myometrium were determined using real-time RT-PCR in each group (control, Porphyromonas gingivalis (P.g.) and P.g. + progesterone (P4)). Experiments were performed in duplicate using eight tissue samples. Statistical analysis was performed using the Mann–Whitney U test. Statistical significance was set at *: p < 0.05, compared P.g. with the control or: †: p < 0.05, P.g. + P4 with P.g., respectively. Values represent the mean ± SD (n = 8).
Control | P.g. | P.g. + P4 | |
---|---|---|---|
Oxytocin receptor | 0.33 ± 0.30 | 1.10 ± 0.56 * | 0.34 ± 0.14 † |
Connexin 43 | 0.34 ± 0.19 | 1.11 ± 0.50 * | 0.44 ± 0.18 † |
PGF2α | 0.25 ± 0.09 | 0.61 ± 0.11 * | 0.45 ± 0.15 |
L type Ca2+ channel | 1.39 ± 0.32 | 3.79 ± 1.77 * | 1.16 ± 0.37 † |
* p < 0.05 (comparison of P.g. with control), † p < 0.05 (comparison of P.g. + P4 with P.g.).