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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Neuron. 2022 Mar 28;110(11):1806–1821.e8. doi: 10.1016/j.neuron.2022.03.003

Figure 4. Latent alphaherpes virus expression in human TG neurons.

Figure 4.

A. Percentage of HSV1_LAT+ neurons or non-neuronal cells in each donor. Dots show percentage of HSV1_LAT+ nuclei in each library and bars indicate the average across libraries.

B. Percentage of each neuronal subtype that are HSV1_LAT+ across all donors.

C. Volcano plot displaying differential gene expression between HSV1_LAT+ and HSV1_LAT- nuclei. HSV1-LAT (n = 115) and the same number of randomly selected cells of the same cell type distribution without detectable expression of HSV1_LAT. Significance is displayed on the Y-axis as -log10 False Discovery Rate (FDR); magnitude of differences is displayed on X-axis as log2 Fold Change (FC).

D. Gene ontology analysis of differentially expressed genes (Log2FC > 1, FDR < 0.05) between HSV1_LAT+ and HSV1_LAT- nuclei. Enrichment is the number of times an ontology term is observed in the differentially expressed gene set over a random gene set of expressed genes.

Bar shows enrichment and color shows P-value.