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. 2022 Jul 31;13(1):1285–1303. doi: 10.1080/21505594.2022.2095716

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — RNA enrichment validity and differential expression between in vivo and in vitro conditions. (a) Quality of enrichment was assessed by correlating the normalized read counts of the enriched in vitro samples (enriched from a mix with RNA from a non-infected kidney) and the non-enriched in vitro samples. Red-labelled data points indicate enrichment bias. (b) Differential expression diagram: more than 1000 genes are up- and downregulated (Log2(fc) ≥1 and ≤1) compared to in vitro conditions. FC: fold-change.