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. 2022 Aug 8;3(10):705–721.e11. doi: 10.1016/j.medj.2022.08.002

Table 2.

Cell binding of various neutralizing antibodies to SARS-CoV-2 and select VOC

Cell binding
Reference clone nAb HEK293 cells
WA-1
Omicron (BA.1)
BA.1.1
EC50 (μg/mL) EC50 (μg/mL) EC50 (μg/mL)
STI-9167 0.014 0.025 0.025
COV2-2130 0.084 0.44 27.2
COV2-2196 0.0087 1.52 0.79
COV2-2130 + COV2-2196 N/D N/D N/D
S309 0.6253 14.5 2.82
LY-CoV1404 0.0587 0.04 0.046

N/D, not determined.

Spike protein from selected VOC expressed on HEK293 cells binding to nAbs is expressed as EC50 (μg/mL).