Table 1.
Relationship of active compounds based on the Anatomical Therapeutic Chemical (ATC) classification and drug categories
| Classification | Unadjusted p-value | |
|---|---|---|
| Drug category | Phenothiazines | 0.0004 |
| Antipsychotic Agents (First Generation [Typical]) | 0.0394 | |
| Level 2 ATC Code | Antimigraine Preparations | 0.0483 |
| Cardiac Glycosides | 0.0082 | |
| Antipsychotics | 0.0006 | |
| Antidepressants | 0.0321 | |
| Agents Against Amebiasis And Other Protozoal Diseases | 0.0303 | |
| Angiotensin II Receptor Blockers (Arbs), Combinations | 0.0483 | |
| Plant Alkaloids And Other Natural Products | 0.0235 | |
| Angiotensin II Receptor Blockers (Arbs), Plain | 0.0235 |
Drug category and therapeutic indication were evaluated for overrepresentation using a one-sided binomial exact test and Benjamini–Hochberg correction for multiple hypothesis testing to calculate the p-value.