Table 3.

Effectiveness outcomes of initiation of medications for opioid use disorder (MOUD) from inpatient medically managed withdrawal programs (detox), and subsequent linkage to outpatient MOUD, showing decrease in fatal overdoses and person-time in active opioid use, and increase in person-time in outpatient MOUD. Results shown for both detox cohort perspective of 40,000 detox patients followed for one year, and full MA OUD population followed for 10 years.

Scenario	Fatal overdoses		Person-time in active opioid use (years)		Person-time on outpatient MOUD (years)
	N (Confidence Interval)	% decrease (from standard of care)	N (Confidence Interval)	% decrease (from standard of care)	N (Confidence Interval)	% increase (from standard of care)
Detox cohort simulation
Standard of Care	550 (498-624)	-	31,700 (29,000-33,700)	-	3,800 (3,300-4,300)	-
Perfect-linkage	412 (388-457)	25.1%	25,200 (23,800-26,100)	21.4%	16,300 (15,000-16,300)	334%
Moderate-linkage	478 (445-533)	13.1%	28,600 (26,400-29,700)	11.0%	10,201 (9,400-10,400)	172%
Massachusetts OUD population simulation
Standard of Care	22,200 (20,470-24,739)	-	2,493,000 (2,282,000-2,604,000)	-	473,000 (444,000-539,000)	-
Perfect-linkage	21,208 (19,734-23,605)	4.5%	2,433,000 (2,249,000-2,526,000)	2.4%	664,000 (606,000-721,000)	40.3%
Moderate-linkage	21,689 (20,126-24,162)	2.3%	2,462,000 (2,268,000-2,562,000)	1.2%	571,000 (528,0000-632,000)	20.7%