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. 2022 Jun 14;17(15):e202000499. doi: 10.1002/cmdc.202000499

Figure 9.

Figure 9

Compounds from each hit series inhibit hyperactivated motility measured by CASA. A. Progesterone‐induced HAM. B. PGE1‐induced HAM. Compounds at the indicated concentration were incubated with human sperm in the presence of progesterone or PGE1 and HAM was measured after 4 h. Data are plotted as a percent of total sperm population and are the mean±SEM of at least 3 individual experiments. *p <0.05, **p <0.005.