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. 2022 Aug 9;10(8):1934. doi: 10.3390/biomedicines10081934

Table 2.

Deregulated ncRNAs in PsO in immune cells and plasma.

Author, Year ncRNA Expression Direct Targets (Indirectly Affected Genes) Cell Type
Immune cells
Zheng et al., 2017 [126] miR-143 Down BCL2 PBMCs
Fu et al., 2015 [125] miR-138 Down RUNX3 CD4+ T cells
Garcıa–Rodrıguez et al., 2016 [128] miR-146a Up TRAF6, IRAK1, (NF-κΒ, IL-6, TNFα) PBMCs
Garcıa–Rodrıguez et al., 2016 [128] miR-21 Up PDCD4 PBMCs
Garcıa–Rodrıguez et al., 2016 [128] miR-155 Up SOCS1 PBMCs
Serum levels
Duan et al., 2019 [130] miR-126 Down - Plasma
Ichihara et al., 2011 [106] miR-424 Down (MEK1, CCNE1) Plasma
Zhao et al., 2014 [129] miR-210 Up FOXP3, (IFN-γ, IL-17, IL-10, TGF-β) Plasma
Magenta et al., 2019 [109] miR-200c Up SIRT1, eNOS, FOXO1 Plasma
Wang et al., 2017 [131] miR-200a Up - Plasma
Borska et al., 2017 [132] miR-31 Up - Plasma
García-Rodríguez et al., 2014 [133] miR-33 Up ABCA1 Plasma
Guo et al., 2013 [134] miR-369-3p Up - Plasma

Abbreviations: ncRNA, non-coding RNA; miR, microRNA; PBMCs, peripheral blood mononuclear cells.