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. 2022 Aug 4;12(8):1075. doi: 10.3390/biom12081075

Table 1.

The levels (lesions/106 nucleosides) of 5′R-cdG, 5′S-cdG, 5′R-cdA, 5′S-cdA, 8-oxo-dG, and 8-oxo-dA in the brain tissues of control SCID and tumor-bearing SCID, 4 weeks of age- and 17 weeks of age, respectively (mean ± standard deviation of six sample measurements).

5′R-cdG 5′R-cdA 5′S-cdG 5′S-cdA 8-oxo-dG 8-oxo-dA
control 4w 0.176 ± 0.011 0.140 ± 0.016 0.205 ± 0.028 0.116 ± 0.014 1.828 ± 0.183 0.202 ± 0.041
control 17w 0.179 ± 0.036 0.146 ± 0.019 0.211 ± 0.024 1,* 0.137 ± 0.012 2,* 1.783 ± 0.208 0.201 ± 0.046
tumor-bearing 4w 0.185 ± 0.018 0.153 ± 0.014 0.213 ± 0.034 0.112 ± 0.014 1.730 ± 0.276 0.201 ± 0.012
tumor-bearing 17w 0.178 ± 0.031 0.140 ± 0.020 0.245 ± 0.025 3,* 0.136 ± 0.012 3,* 1.903 ± 0.234 0.216 ± 0.046

1 Comparison between control 17-week-old mice vs. tumor-bearing 17-week-old mice, 2 Comparison between control 4-week-old mice vs. control 17-week-old mice, 3 Comparison between tumor-bearing 4-week-old mice vs. tumor-bearing 17-week-old mice. Statistical significance: * (p < 0.05).