Skip to main content
. 2022 Aug 12;14(16):3314. doi: 10.3390/nu14163314

Figure 5.

Figure 5

Effect of L7Gn on BDNF mRNA expression levels in the hippocampus of sleep-deprived mice. (A) L7Gn was dissolved in 70% PEG-saline, and FXT was dissolved in 0.9% physiological saline. Mice were administered vehicle (70% PEG), L7Gn (0.3, 1, and 3 mg/kg), or FXT (20 mg/kg) once daily for five days. (A) The mRNA expression of BDNF was assessed using qRT-PCR. (B) ANA-12 was dissolved in 1% DMSO. Mice were administered vehicle (70% PEG), L7Gn (3 mg/kg), or ANA-12 (0.5 mg/kg) once daily for five days. (B) The mRNA expression of BDNF was assessed via qRT-PCR. (A) BDNF: (one-way ANOVA: F (5, 14) = 2.734, p = 0.0631) (B) BDNF: (one-way ANOVA: F (3, 11) = 11.29, p = 0.0011). All data are presented as mean ± SEM (n = 3–4/group). * p < 0.05, significantly different from the control group. # p < 0.05, significantly different from the vehicle group. $ p < 0.05, significantly different from the L7Gn (3 mg/kg) group. CTL, control; Veh, vehicle; FXT, fluoxetine.