Table 9.
Parameters (Unit) | Groups | Baseline | At 6 Months | At 12 Months | p-Value |
---|---|---|---|---|---|
GFR (mL/min/1.73 m2) | Male | 85.8 (67.6–99.7) | 94.47 (69.9–100.2) | 91.04 (74.24–106.67) | 0.004 |
Female | 90.1 (64–93.7) | 83.28 (69.67–94.46) | 80.99 (68.8–95.75) | 0.342 | |
Serum creatinine (mg/dL) | Male | 1 (0.9–1.2) | 0.98 (0.87–1.25) | 0.96 (0.84–1.2) | 0.004 |
Female | 0.8 (0.7–1.1) | 0.85 (0.73–1.02) | 0.85 (0.71–1) | 0.15 | |
Serum phosphorous (mg/dL) | Male | 3.7 (3.2–4.1) | 3.32 (2.78–3.97) | 3.31 (2.87–4) | 0.171 |
Female | 3.5 (2.8–3.8) | 3.26 (2.62–3.7) | 3.14 (2.72–3.72) | 0.089 | |
iPTH (pg/mL) | Male | 51.5 (43.3–60.1) | 55.03 (48.31–61) | 51.02 (43.76–62.32) | 0.003 |
Female | 51.8 (44.7–60.2) | 55.05 (48.21–63.9) | 52.42 (47.03–61.87) | 0.005 | |
FGF-23 (pg/mL) | Male | 57.3 (53.6–61.6) | 56.22 (51.81–58.84) | 52.49 (46.98–60.43) | 0.072 |
Female | 55.2 (52.2–59.1) | 56.15 (51.44–61.62) | 55.53 (49.33-59.1) | 0.009 | |
sKlotho (pg/mL) | Male | 702.8 (648.7–811.7) | 802.4 (734.73–914.98) | 819.22 (682.73–1024.1) | <0.001 |
Female | 703.6 (673.9–840.7) | 893 (751.91–983.19) | 853.85 (762.54–1020.45) | <0.001 | |
Urinary phosphorous (mg/day) | Male | 661 (476.6–798.6) | 597.1 (464.73–714.24) | 692.37 (534.29–791.48) | 0.136 |
Female | 638.9 (403.4–804.3) | 585.5 (357.39–725.81) | 699.7 (568.21–789.45) | 0.071 | |
Urinary protein (mg/mL) | Male | 20.5 (18.3–22.5) | 21.06 (18.42–25.56) | 18.95 (16.91–22.19) | 0.003 |
Female | 19.4 (15.8–22.5) | 19.63 (16.45–22) | 18.58 (15.82–22.18) | 0.835 | |
Serum calcium (mg/dL) | Male | 8.9 (8.6–9.1) | 9.09 (7.02–10.18) | 8.5 (7.95–10.3) | 0.645 |
Female | 9 (8.3–9.3) | 8.95 (8.04–9.44) | 8.8 (7.3–9.76) | 0.795 | |
Vitamin D (ng/mL) | Male | 28.1 (19.8–32.4) | 26.3 (19.43–30.98) | 26.32 (21.88–30.12) | 0.518 |
Female | 27.4 (18.7–30.8) | 26.6 (23.7–32.4) | 27.4 (24.38–33.09) | 0.819 | |
Dietary Protein intake | Male | 43.7 (38.7–52.1) | 40.89 (38.43–46.1) | 41.21(38.44–45.32) | 0.001 |
Female | 40.3 (36.6–47.9) | 39.31 (34.75–43.41) | 38.4 (35.08–43.1) | 0.002 | |
Dietary phosphorous intake (mg/day) | Male | 1161.7 (883.5–1376.1) | 1027.56 (905.01–1194.04) | 957 (887.69–1095) | 0.03 |
Female | 1140.9 (867.6–1238.9) | 967.35 (824.56–1148.85) | 871.73 (842–1003) | <0.001 |
p value was calculated by Friedman test.