Table 1.
Descriptive and resting variables.
| Controls (n = 16) | Patients (n = 34) | ||||
|---|---|---|---|---|---|
| Age (years), mean ± SD | 56 ± 10 | 51 ± 10 | |||
| Breast cancer stage, n (%) | n/a | ||||
| I | 4 (12%) | ||||
| II | 25 (74%) | ||||
| III | 5 (15%) | ||||
| Chemotherapy regimen | n/a | ||||
| Anthracycline-containing, n (%) | 24 (71%) | ||||
| Anthracycline dose (mg/m2), median | 301 | ||||
| Trastuzumab-containing, n (%) | 9 (26%) | ||||
| Trastuzumab dose (mg/kg), median | 107 | ||||
| Radiation therapy, n (%) | n/a | ||||
| Left sided | 18 (53%) | ||||
| Dose (cGy), median | 4500 | ||||
| Right sided | 13 (38%) | ||||
| None | 3 (9%) | ||||
| Controls | Pre-chemotherapy | Mid-chemotherapy | End-chemotherapy | One year | |
|---|---|---|---|---|---|
| Mean ± SD | |||||
| Body mass (kg) | 74.9 ± 11.7 | 73.3 ± 16.6 | 74.1 ± 17.4 | 73.5 ± 15.9 | 73.9 ± 16.8 |
| Body mass index (kg/m2) | 27.9 ± 4.9 | 27.3 ± 5.4 | 27.6 ± 5.4 | 27.4 ± 5.1 | 27.6 ± 5.3 |
| Systolic blood pressure (mmHg) | 114 ± 11 | 112 ± 12 | 109 ± 10a | 109 ± 11a | 113 ± 17 |
| Diastolic blood pressure (mmHg) | 69 ± 6 | 69 ± 9 | 65 ± 8a | 66 ± 9a | 68 ± 13 |
| Arterial O2 saturation (%) | 98 ± 2 | 99 ± 1 | 99 ± 1 | 98 ± 2 | 98 ± 2 |
Different from pre-chemotherapy (P ≤ .05).