Key resources table

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
RB-C2	Santa Cruz Biotech	sc-74562; RRID:AB_2177334
RB phospho S807	Abcam	ab47762; RRID:AB_882296
p107-D3P3C	Cell Signaling Technology	#89798; RRID:AB_2800144
Anti-OctA-Probe H-5	Santa Cruz Biotech	sc-166355; RRID:AB_2017593
Bacterial and virus strains
E. coli BL21(DE3)	New England Biolabs	Cat#: C2527
Chemicals, peptides, and recombinant proteins
Synthetic peptides for AlphaScreen	Belyntic GmbH	See Table S1
Synthetic peptides for X-ray crystallography	Genscript Biotech	See Figure 1 and Table S1
Deposited data
p107-ARID4A structure	This paper	PDB: 7SMC
p107-EID1 structure	This paper	PDB: 7SMD
p107-HDAC1 structure	This paper	PDB: 7SME
p107-HDAC1-3X structure	This paper	PDB: 7SMF
Experimental models: Cell lines
HCT116	ATCC	ATCC#: CCL-247
Oligonucleotides
See Table S2 for synthetic oligonucleotides used for site-directed mutagenesis	This paper	N/A
Recombinant DNA
FLAG-HDAC1 (human)	Emiliani et al., 1998	Addgene Plasmid # 13820
p107 pocket domain	Guiley et al., 2015	Request from lead contact
Rb pocket domain	Guiley et al., 2015	Request from lead contact
Software and algorithms
XDS	Kabsch, 2010	https://xds.mr.mpg.de
XIA2	Winter, 2010	https://xia2.github.io
AIMLESS	Evans, 2006	https://www.ccp4.ac.uk
CCP4 program suite	Winn et al., 2011	https://www.ccp4.ac.uk
MOLREP	Vagin and Teplyakov, 2010	https://www.ccp4.ac.uk
COOT	Emsley and Cowtan, 2004	https://www.ccp4.ac.uk
Phenix	Adams et al., 2010	http://www.phenix-online.org
proFit7	Quantumsoft, Zurich, Switzerland	https://www.quansoft.com