Extended Data Fig. 9. Proportion of CD8 memory and dysfunction clusters in CAR-T cells prepared by different methods.
a, Heat map showing scaled expression of memory, dysfunction and cytotoxicity genes in two CD8+ T cell clusters. The gene set variation analysis (GSVA) scores of CD8 memory, dysfunction and cytotoxicity signatures are shown at the top. b, tSNE plots showing C1 and C2 in each sample. c, Percentages of C1 and C2 in mixed samples. d-e, Comparison of C1 and C2 proportion between CAR+ and CAR− cells in mixed (d) and individual (e) samples.